The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2000
Filed:
Feb. 26, 1998
Applicant:
Inventors:
Gary J Nabel, Ann Arbor, MI (US);
Zhi-yong Yang, Ann Arbor, MI (US);
Elizabeth G Nabel, Ann Arbor, MI (US);
Assignee:
University of Michigan, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
514 44 ; 4353201 ; 435375 ; 435440 ; 435455 ; 435475 ; 435476 ;
Abstract
The p21 gene encodes a cyclin dependent kinase inhibitor which affects cell cycle progression, but the role of this gene product in altering tumor growth has not been established. The present inventors have now discovered that the growth of malignant cells in vivo is inhibited by expression of p21. Expression of p21 resulted in an accumulation of cells in G.sub.0 /G.sub.1, alteration in morphology, and cell differentiation.
Nabel, Gary. (2000). Methods for treating cancers and restenosis with p21 (U.S. Patent No. 6057300). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6057300
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile