The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2000

Filed:

Dec. 10, 1996
Applicant:
Inventors:

Robert E Hancock, Vancouver, CA;

Nedra Karunaratne, Kandy, LK;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514 12 ; 514 13 ; 530324 ; 530326 ;
Abstract

A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include NH.sub.2 --KWKSFIKKLTTAVKKVLTTGLPALIS--COOH (SEQ ID NO:1) and NH.sub.2 --KWKSFIKKLTSAAKKVVTTAKPLISS--COOH (SEQ ID NO:2). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.


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