The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2000

Filed:

May. 07, 1997
Applicant:
Inventors:

Peter T Lansbury, Jr, Brookline, MA (US);

Hogyu Han, Seoul, KR;

Cheon-Gyu Cho, Seoul, KR;

Weiguo Zhen, Waltham, MA (US);

James D Harper, Cambridge, MA (US);

Alan Davison, West Roxbury, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07F / ;
U.S. Cl.
CPC ...
424-111 ; 424-91 ; 534 10 ; 534 12 ; 534 14 ; 534883 ; 556 45 ;
Abstract

Novel organometallic compounds for binding amyloid are described. Methods using such compounds for determining by imaging the localization or quantification of amyloid fibrils in a mammal, for diagnosing the degree of progression of Alzheimer's disease in a mammal, for monitoring the response to a therapy in a mammal having Alzheimer's disease, for identifying an agent useful for treating Alzheimer's disease, for treating Alzheimer's disease, and for detecting the presence of the infectious form of the prion protein, are also described.


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