The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2000

Filed:

May. 07, 1999
Applicant:
Inventors:

Ronald Hans Plasterk, Bussum, NL;

Domenico Valerio, Leiden, NL;

Govert Johan Schouten, Leiden, NL;

Hendricus Gerhard van Luenen, Amsterdam, NL;

Jan C Vos, Amsterdam, NL;

Assignees:

Het Nederlands Kanker Instituut, Amsterdam, NL;

IntroGene B.V., Leiden, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435462 ; 4353201 ; 435325 ; 536 231 ;
Abstract

The present invention provides novel elements for improving genetic engineering techniques for producing recombinant nucleic acid molecules and/or recombinant cells. The novel elements are capable of integrating desired nucleic acid material into other nucleic acid materials, specifically into the genome of a host cell. The novel elements are derived from or based on transposons, in particular from the Tc/Mariner superfamily. In particular, the essential elements of Tc1 enabling excision and pasting of the desired nucleic acid material are provided, together with the relevant transposase activity in cis or in trans.


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