The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2000
Filed:
Nov. 12, 1997
Applicant:
Inventors:
Robert Siman, Wilmington, DE (US);
Donna Bozyczko-Coyne, Landenberg, PA (US);
Sheryl L Meyer, Collegeville, PA (US);
Ratan Venkatraman Bhat, West Chester, PA (US);
Assignee:
Cephalon, Inc., West Chester, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ; C07K / ;
U.S. Cl.
CPC ...
435-71 ; 435-722 ; 435-721 ; 435-723 ; 435-724 ; 435-79 ; 435-792 ; 435-793 ; 435-794 ; 435-795 ; 436501 ; 436503 ; 436504 ; 436515 ; 436536 ; 436544 ; 436545 ; 436546 ; 5303879 ;
Abstract
Methods for the biochemical and immunohistochemical detection of cell apoptosis are described. The methods utilize the detection and measurement of polypeptide fragments generated during apoptosis. Conditions associated with apoptosis may be detected by the methods of this invention. Methods are also presented for the screening of potential therapeutic compounds which inhibit or stimulate apoptosis. Kits for detection of apoptosis and diagnosis of diseases are also provided.