The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2000
Filed:
Mar. 26, 1999
Wolfgang Grell, Biberach, DE;
Helmut Wittneben, Maselheim, DE;
Jacobus Constantinus van Meel, Mittelbiberach, DE;
Norbert Redemann, Biberach, DE;
Rainer Walter, Biberach, DE;
Armin Heckel, Biberach, DE;
Frank Himmelsbach, Mittelbiberach, DE;
Robert Haigh, Hants, GB;
Boehringer Ingelheim Pharma KG, Ingelheim, DE;
Abstract
The present invention relates to indolinones of general formula ##STR1## wherein R.sub.1 to R.sub.3 are defined in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on various kinases and cycline/CDK complexes and on the proliferation of various tumour cells, pharmaceutical compositions containing these compounds, their use and processes for preparing them.