The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2000
Filed:
Dec. 23, 1992
Dennis W Adair, Suisun, CA (US);
Karl M Johnson, Bozeman, MT (US);
Earl R Kern, Birmingham, AL (US);
Oclassen Pharmaceuticals, Inc., San Rafael, CA (US);
Abstract
The present invention relates to pharmaceutical compositions useful for the treatment of subjects suffering from an infection or disease caused by herpes virus strains that are resistant to treatment with acyclovir. In particular, it has been discovered that the low dosage amounts of 1-(2'-deoxy-2'-fluoro-.beta.-D-arabinofuranosyl)-5-iodouracil (FIAU) are effective in inhibiting replication of acyclovir-resistant HSV strains. The present invention is also directed to methods of the preparation of pharmaceutical antiviral compositions and to the methods of their use in the treatment of infection or disease.