logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6036953 B1

PDFFull Text
Date of Patent:
Mar. 14, 2000

Filed:

Nov. 25, 1997

Heterologous antigens in live cell v. cholerae strains

Applicant:
Inventors:

Edward T Ryan, Quincy, MA (US);

Stephen B Calderwood, Wellesley, MA (US);

Assignee:

The General Hospital Corporation, Boston, MA (US);

Attorney:

Fish & Richardson P.C.

Primary Examiner:

James C Housel

Assistant Examiner:

S Devi

Int. Cl.
CPC ...
A01N / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424 932 ; 424 931 ; 424 934 ; 424 9341 ; 4241921 ; 424-934 ; 4242341 ; 4242361 ; 4242611 ; 4242391 ; 4242471 ; 514837 ;
Abstract

Disclosed is a V. cholerae cell containing a DNA encoding a fusion polypeptide that includes a heterologous antigenic polypeptide sequence such as a portion of C. difficile toxin A. The fusion polypeptide also includes one of the following: (i) an E. coli hemolysin A subunit (wich is coexpressed with sequences encoding hemolysin B and D subunits); (ii) a secretion signal sequence and cholera toxin A2 subunit (which is coexpressed with cholera toxin B subunit); or (iii) cholera toxin B subunit.

Find Patent Forward Citations

Ryan, Edward. (2000). Heterologous antigens in live cell v. cholerae strains (U.S. Patent No. 6036953). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6036953

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…