The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2000

Filed:

Dec. 11, 1997
Applicant:
Inventors:

Philip J Barr, Oakland, CA (US);

Daniel V Santi, San Francisco, CA (US);

Gary W Ashley, Alameda, CA (US);

Rainer Ziermann, San Mateo, CA (US);

Assignee:

KOSAN Biosciences, Inc., Burlinggame, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435148 ; 435 691 ; 435 697 ; 43525233 ; 43525421 ; 4353201 ; 435471 ; 435477 ; 435483 ; 435484 ; 435486 ; 435488 ; 536 232 ; 536 234 ; 536 237 ;
Abstract

Hybrid and novel polyketide synthases and polyketides are produced by use of a multiple vector system. The combinatorial possibilities offered by placing the various catalytic activities of PKS systems on separate vectors permits the construction of improved libraries of PKS and polyketides. In addition, polyketides can be produced in hosts that ordinarily do not produce polyketides by supplying, along with an expression system for the desired PKS, an expression system for holo ACP synthase.


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