The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2000
Filed:
Nov. 05, 1997
Applicant:
Inventors:
Robert W Chesnut, Cardiff, CA (US);
Margaret J Polley, La Jolla, CA (US);
James C Paulson, Del Mar, CA (US);
S Tarran Jones, Radlett, GB;
Jose W Saldanha, Middlesex, GB;
Mary M Bendig, London, GB;
Michael Kriegler, Rancho Santa Fe, CA (US);
Carl Perez, San Diego, CA (US);
Robert Bayer, San Diego, CA (US);
Michael Nunn, San Diego, CA (US);
Assignee:
Cytel Corporation, San Diego, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
4241531 ; 424-149 ; 4241301 ; 4241331 ; 4241391 ; 4241431 ; 4241521 ; 4241721 ; 4241781 ; 4241411 ; 5303871 ; 5303873 ; 5303882 ; 53038822 ; 5303887 ; 5303913 ; 5303914 ; 435 7021 ; 435326 ; 435343 ; 435346 ; 536 2353 ;
Abstract
The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.