The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 29, 2000
Filed:
Jun. 30, 1998
Applicant:
Inventors:
Fatih M Uckun, White Bear Lake, MN (US);
Rakesh Vig, Little Canada, MN (US);
Assignee:
Wayne Hughes Institute, Roseville, MN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514 51 ; 514 49 ; 514 50 ; 514885 ; 536 261 ; 536 268 ; 536 282 ;
Abstract
Aryl phosphate derivatives of d4T with para-bromo substitution on the aryl group show markedly increased potency as anti-HIV agents without undesirable levels of cytotoxic activity. In particular, these derivatives are potent inhibitors of HIV reverse transcriptase. In a preferred aspect of the present invention, the phosphorus of the aryl phosphate group is further substituted with an amino acid residue that may be esterified or substituted, such as a methoxy alaninyl group.
Uckun, Fatih. (2000). Aryl phosphate derivatives of d4t having anti-hiv activity (U.S. Patent No. 6030957). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6030957
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile