The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 29, 2000
Filed:
Mar. 17, 1998
Barry S Cooperman, Penn Valley, PA (US);
Ralph F Hirschmann, Blue Bell, PA (US);
Amos B Smith, III, Merion, PA (US);
Paul Laub, San Jose, CA (US);
Setsuya Sasho, Shizuoka-Ken, JP;
Paul A Sprengeler, Merion, PA (US);
Bari A Barwis, Philadelphia, PA (US);
Alison Fisher, Blue Bell, PA (US);
Shrikumar Nair, Upper Darby, PA (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
The invention relates to compositions which are useful for inhibiting ribonucleotide reductase enzymes, including the mammalian ribonucleotide reductase enzyme. The compositions include, but are not limited to, linear peptides, cyclic peptides, peptide analogs, and peptidomimetics. Methods of using the compositions of the invention to treat cancer and viral and bacterial infections are disclosed.