The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 29, 2000

Filed:

Apr. 16, 1996
Applicant:
Inventors:

Jutta Muller-Derlich, Germering, DE;

Robert Koll, Kirchheim, DE;

Wolfgang Bohm, Munchen, DE;

Franz A Bieber, Unterschleissheim, DE;

Reiner Spaethe, Starnberg, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
4241401 ; 4241531 ; 4241561 ; 4241731 ; 4241451 ; 4241581 ; 424 9371 ; 435 7021 ; 435 696 ; 5303871 ; 5303882 ; 53038825 ;
Abstract

The invention provides a method to prevent or ameliorate hyperacute or acute rejection of a human donor organ transplanted to a human recipient. Hyperacute rejection would normally occur after a human subject receives a transplanted human organ against which the subject has preformed anti-HLA antibodies. Acute rejection occurs when the recipient of a human organ forms antibodies against that organ after transplant. The invention method comprises passing the plasma of the recipient over a sterile and pyrogen-free column coupled to anti-human immunoglobulin antibodies which bind to and remove a significant portion of the immunoglobulin from the subject's plasma.


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