The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2000

Filed:

Apr. 30, 1997
Applicant:
Inventors:

Jolie Anne Bastian, Beech Grove, IN (US);

Nickolay Yuri Chirgadze, Carmel, IN (US);

Michael Lyle Denney, Franklin, IN (US);

Matthew Joseph Fisher, Carmel, IN (US);

Robert James Foglesong, Durham, NC (US);

Richard Waltz Harper, Indianapolis, IN (US);

Mary George Johnson, Durham, NC (US);

Valentine Joseph Klimkowski, Carmel, IN (US);

Todd Jonathan Kohn, Fishers, IN (US);

Ho-Shen Lin, Indianapolis, IN (US);

Michael Patrick Lynch, Raleigh, NC (US);

Jefferson Ray McCowan, Indianapolis, IN (US);

Alan David Palkowitz, Carmel, IN (US);

Michael Enrico Richett, Indianapolis, IN (US);

Daniel Jon Sall, Greenwood, IN (US);

Gerald Floyd Smith, Indianapolis, IN (US);

Kumiko Takeuchi, Indianapolis, IN (US);

Jennifer Marie Tinsley, Martinsville, IN (US);

Minsheng Zhang, Nutley, NJ (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514422 ; 514212 ; 5142335 ; 514318 ; 514326 ; 514380 ; 514443 ; 540602 ; 544141 ; 546194 ; 546202 ; 548518 ; 548523 ; 548525 ; 548243 ; 549 58 ;
Abstract

This application relates to the use as thrombin inhibitors, coagulation inhibitors and thromboembolic disorder agents of diamines of formula I as defined herein. It also provides novel compounds of formula I, processes and intermediates for their preparation, and pharmaceutical formulations comprising the novel compounds of formula I.


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