The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2000

Filed:

May. 30, 1995
Applicant:
Inventors:

Ake Lernmark, Seattle, WA (US);

Allan E Karlsen, Valby, DK;

Catherine E Grubin, Seattle, WA (US);

William Hagopian, Seattle, WA (US);

Patrick J O'Hara, Seattle, WA (US);

Donald C Foster, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12P / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
435195 ; 435691 ; 530324 ; 530326 ; 530329 ;
Abstract

Human pancreatic islet cell glutamic acid decarboxylase (GAD), an autoantigen involved in the development of insulin-dependent diabetes mellitus (IDDM), has been cloned, sequenced and expressed by recombinant means. Recombinant human islet cell GAD polypeptides and antibodies specific to the GAD polypeptides can be used in methods of diagnosis and treatment, including use in immunoadsorptive therapy and the induction of immune tolerance.


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