The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2000

Filed:

Jun. 05, 1995
Applicant:
Inventors:

Jayvardhan Pandit, Mystic, CT (US);

Jarmila Jancarik, Walnut Creek, CA (US);

Sung-Hou Kim, Moraga, CA (US);

Kirston Koths, El Cerrito, CA (US);

Robert Halenbeck, San Rafael, CA (US);

Anna Lisa Fear, Oakland, CA (US);

Eric Taylor, Oakland, CA (US);

Ralph Yamamoto, Martinez, CA (US);

Andrew Bohm, Armonk, NY (US);

Assignee:

Chiron Corporation, Emeryville, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
435-72 ; 435375 ; 435 695 ; 4351723 ; 554211 ; 530351 ; 530412 ; 530418 ; 530419 ; 530421 ;
Abstract

The present invention is directed to methods for crystallizing macrophage colony stimulating factor. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to methods for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, soluble and functional M-CSF receptor.


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