The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2000
Filed:
Jan. 09, 1998
Applicant:
Inventors:
Heinz-Werner Kleemann, Bishchofsheim, DE;
Joachim Brendel, Bad Vilbel, DE;
Jan-Robert Schwark, Frankfurt, DE;
Andreas Weichert, Egelsbach, DE;
Hans-Jochen Lang, Hofheim, DE;
Udo Albus, Florstadt, DE;
Wolfgang Scholz, Eschborn, DE;
Assignee:
Hoechst Aktiengesellschaft, Frankfurt am Main, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ;
U.S. Cl.
CPC ...
514595 ; 564 56 ; 564230 ; 546139 ; 546152 ; 546333 ; 514307 ; 514311 ; 514357 ;
Abstract
There are described compounds of the formula I ##STR1## in which the substituents R(1) to R(7) and X have the meanings shown in the claims, and their pharmaceutically tolerable salts. These are effective inhibitors of the cellular sodium proton antiporter (Na.sup.+ /H.sup.+ exchanger). They are therefore outstandingly suitable for the treatment of all diseases which can be attributed to increased Na.sup.+ /H.sup.+ exchange.