The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2000
Filed:
Jul. 23, 1998
Applicant:
Inventors:
Hans Holmegaard So slashed.rensen, Virum, DK;
Ole Hvilsted Olsen, Br.o slashed.nsh.o slashed.j, DK;
Lars Thim, Gentofte, DK;
Christensen Thorkild, Aller.o slashed.d, DK;
Per Balschmidt, Esperg.ae butted.rde, DK;
Assignee:
Novo Nordisk A/S, Bagsvaerd, DK;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514 12 ; 514-2 ; 514 21 ; 530399 ; 530397 ; 530362 ; 530363 ; 530324 ; 435 691 ;
Abstract
A pharmaceutical formulation comprising a growth hormone pretreated with zinc and optionally lysine or calcium ions shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.