The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2000

Filed:

Jan. 23, 1997
Applicant:
Inventor:

Daniel Robert Gentry, Pottstown, PA (US);

Assignee:

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435 693 ; 435 697 ; 4352523 ; 43525411 ; 4353201 ; 435325 ; 536 232 ; 536 234 ; 536 237 ; 935-3 ; 935-6 ; 935 12 ;
Abstract

greA polypeptides and DNA (RNA) encoding such greA and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such greA for the treatment of infection, particularly bacterial infections. Antagonists against such greA and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of greA nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding greA/greB gene family and for detecting the polypeptide in a host.


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