The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2000
Filed:
Sep. 25, 1998
Applicant:
Inventors:
Jeffrey T Beckvermit, Berthoud, CO (US);
Chi Tu, Louisville, CO (US);
Assignee:
NeXstar Pharmaceuticals, Inc., Boulder, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 2711 ; 536 2714 ; 536 272 ; 536 273 ; 536 274 ; 536 275 ; 536 276 ; 536 2761 ; 536 2762 ; 536 2763 ; 536 277 ; 536 278 ; 536 2781 ; 536 282 ; 536 283 ; 536 284 ; 536 285 ; 536 2851 ; 536 2852 ; 536 2853 ; 536 2854 ; 536 2855 ;
Abstract
This invention discloses a method for the preparation of 2'-modified nucleosides, using a palladium catalyst and an alkene functionalized with a heteroatom. Included in the invention are the novel pyrimidines and purines that can be prepared according to the method of the invention and oligonucleotides containing said modified pyrimidines and purines.