The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2000

Filed:

Dec. 22, 1997
Applicant:
Inventors:

Donald Joseph Pinto, Newark, DE (US);

James Russell Pruitt, Landenberg, PA (US);

Joseph Cacciola, Newark, DE (US);

John Matthew Fevig, Lincoln University, PA (US);

Qi Han, Wilmington, DE (US);

Michael James Orwat, Hockessin, DE (US);

Mimi Lifen Quan, Newark, DE (US);

Karen Anita Rossi, Newark, DE (US);

Assignee:

DuPont Pharmaceuticals Company, Wilmington, DE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514406 ; 5142365 ; 514255 ; 514326 ; 514341 ; 514359 ; 514371 ; 514381 ; 514383 ; 514394 ; 514397 ; 514407 ; 544140 ; 544371 ; 546211 ; 5462754 ; 548200 ; 548253 ; 548255 ; 5482662 ; 5483061 ; 5483124 ; 5483641 ; 5483651 ; 5483657 ; 5483697 ; 5483721 ; 5483725 ; 5483741 ;
Abstract

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D may be C(.dbd.NH)NH.sub.2, which are useful as inhibitors of factor Xa.


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