The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2000

Filed:

Jun. 25, 1996
Applicant:
Inventors:

Ying Bao, Sunnyvale, CA (US);

Amy Boggs, Menlo Park, CA (US);

Pamela R Contag, San Jose, CA (US);

Nancy A Federspiel, Menlo Park, CA (US);

Alan Hebert, Menlo Park, CA (US);

Scott Hecker, Los Gatos, CA (US);

Francois Malouin, Los Gatos, CA (US);

Assignee:

Microcide Pharmaceuticals, Inc., Mountain View, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435-4 ; 435-6 ; 4352521 ; 536 237 ; 536 241 ;
Abstract

Methods are provided for screening for potential inhibitors of bacterial, or other microbial, global pathogenesis gene regulators and other gene regulators. Methods are also provided for treating microbial (e.g., bacterial) infections using such inhibitors. Also included are pharmaceutical compositions containing such inhibitors. The screening methods involve detecting whether the activity of a global pathogenesis gene regulator is altered in the presence of a test compound.


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