The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 25, 2000

Filed:

Nov. 10, 1997
Applicant:
Inventors:

Riaz Khan, Sonning, GB;

Paul A Konowicz, Farnham, GB;

Antonella Flaibani, Udine, IT;

Valentina Gombac, Trieste, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C08B / ;
U.S. Cl.
CPC ...
514 54 ; 536 53 ; 536 553 ; 424-173 ; 424-935 ; 424-943 ;
Abstract

Hyaluronic acid or hyaluronic acid ester derivatives, wherein one or more hydroxy functions of its 1,4.beta.-D-glucuronic acid and 1,3-.beta.-N-acetyl-D-glucosamine alternating repeating units are esterified with a carboxyl group of succinic acid to form the succinic hemiester of hyaluronic acid or hyaluronic acid esters. These derivatives are used to prepare the corresponding heavy metal salts of succinic hemiesters of hyaluronic acid or with hyaluronic acid partial or total esters. These salts are used as active ingredients in the preparation of pharmaceutical compositions to be used as antibacterial and disinfectant agents for the treatment of wounds, burns and ophthalmia or as antiinflammatory agents in particular for the preparation of pharmaceutical compositions for the treatment of osteoarticular disorders.


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