The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2000
Filed:
Feb. 09, 1996
Applicant:
Inventors:
Susan Wollowitz, Walnut Creek, CA (US);
Stephen T Isaacs, Orinda, CA (US);
Henry Rapoport, Berkeley, CA (US);
Hans Peter Spielmann, Berkeley, CA (US);
Aileen Nerio, Santa Clara, CA (US);
Assignee:
Cerus Corporation, Concord, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; A01N / ; C12N / ;
U.S. Cl.
CPC ...
435-2 ; 435238 ; 549282 ; 424 9372 ;
Abstract
Psoralen compounds are synthesized which have substitutions on the 4, 4', 5', and 8 positions of the psoralen, which permit enhanced binding to nucleic acid of pathogens. Higher psoralen binding levels and lower mutagenicity are described, resulting in safer, more efficient, and reliable inactivation of pathogens in blood products. The invention contemplates inactivation methods using the new psoralens which do not compromise the function of blood products for transfusion.