The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2000

Filed:

Nov. 07, 1997
Applicant:
Inventors:

Gary Lowell Engel, Greenwood, IN (US);

Nagy Alphonse Farid, Lebanon, IN (US);

Margaret Mary Faul, Zionsville, IN (US);

Michael Robert Jirousek, Indianapolis, IN (US);

Lori Ann Richardson, Indianapolis, IN (US);

Leonard Larry Winneroski, Jr, Greenwood, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; A01N / ; C07D / ;
U.S. Cl.
CPC ...
514183 ; 514185 ; 540454 ; 540467 ;
Abstract

This invention provides novel bis-indolylmaleimide macrocycle derivatives of the formula: and solvates thereof. The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.


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