The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2000
Filed:
Dec. 04, 1997
Applicant:
Inventors:
Albert Gyorkos, Westminster, CO (US);
Lyle W Spruce, Chula Vista, CA (US);
Assignee:
Cortech Inc., Bedminster, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
514 18 ; 514 19 ; 514213 ; 514214 ; 514220 ; 514221 ; 530331 ; 540495 ; 540502 ; 540503 ; 540506 ; 540507 ; 540508 ; 540509 ; 540510 ; 540511 ; 540513 ; 540520 ; 540523 ;
Abstract
The present invention relates to certain substituted oxadiazole, thiadiazole, and triazoles, in particular those including a cycloheptane structure, that are useful as serine protease inhibitors, including inhibitors for human neutrophil elastase. Compounds of the invention are useful in treating conditions such as adult respiratory distress syndrome, septic shock, and multiple organ failure.