The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2000

Filed:

Jan. 27, 1997
Applicant:
Inventors:

Rajender Kamboj, Mississauga, CA;

Stephen L Nutt, Etobicoke, CA;

Lee Shekter, Toronto, CA;

Michael A Wosnick, Thornhill, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ;
U.S. Cl.
CPC ...
530350 ; 530300 ; 530395 ; 435 691 ; 536 235 ;
Abstract

Neurotransmission by excitatory amino acids (EAAs) such as glutamate is mediated via membrane-bound surface receptors. DNA coding for one family of these receptors, of the kainate binding type of EAA receptors, has now been isolated and the receptor protein characterized. Herein described art recombinant cell lines which produce the EAA receptor as a heterologous membrane-bound product. Also described are related aspects of the invention, which are of commercial significance. Included is use of the cell lines as a tool for discovery of compounds which modulate EAA receptor stimulation.


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