The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2000
Filed:
Dec. 04, 1997
Applicant:
Inventors:
Malcolm Maccoss, Freehold, NJ (US);
Sander G Mills, Woodbridge, NJ (US);
Shrenik K Shah, Metuchen, NJ (US);
Yuan-Ching P Chiang, Scotch Plains, NJ (US);
Patrick T Dunn, Woodbridge, NJ (US);
Hiroo Koyama, Westfield, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514278 ; 5142265 ; 514258 ; 514373 ; 514409 ; 544-6 ; 544230 ; 546 17 ; 546 18 ; 548207 ; 548409 ; 548410 ;
Abstract
Disclosed are spiro-substituted azacycles of formula I are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of formula I are shown to be neurokinin antagonists.