The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2000
Filed:
Mar. 07, 1995
Richard E Moore, Honolulu, HI (US);
Marcus A Tius, Kailua, HI (US);
Russell A Barrow, Honolulu, HI (US);
Jian Liang, Honolulu, HI (US);
Thomas H Corbett, Grosse Point, MI (US);
Frederick A Valeriote, Shelby Township, MI (US);
Trimurtulu Golakoti, Honolulu, HI (US);
Thomas K Hemscheidt, Honolulu, HI (US);
The University of Hawaii, Honolulu, HI (US);
Wayne State University, Detroit, MI (US);
Abstract
A cryptophycin compound is provided having the structure: ##STR1## Further provided are methods of producing cryptophycins by total synthesis and methods of using cryptophycins in pharmaceuticals. It is a further object of this invention to use cryptophycins to inhibit the proliferation of mammalian cells. Moreover, methods of using cryptophycins to treat neoplasia is also provided.