The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2000
Filed:
Oct. 07, 1997
Glenn Albrecht, Redwood City, CA (US);
Sydney Brenner, Cambridge, GB;
Robert B DuBridge, Belmont, CA (US);
David H Lloyd, Daly City, CA (US);
Michael C Pallas, San Bruno, CA (US);
Lynx Therapeutics, Inc., Hayward, CA (US);
Abstract
The invention provides a method of nucleic acid sequence analysis based on the ligation of one or more sets of encoded adaptors to the terminus of a target polynucleotide. Encoded adaptors whose protruding strands form perfectly matched duplexes with the complementary protruding strands of the target polynucleotide are ligated, and the identity of the nucleotides in the protruding strands is determined by an oligonucleotide tag carried by the encoded adaptor. Such determination, or 'decoding' is carried out by specifically hybridizing a labeled tag complement to its corresponding tag on the ligated adaptor.