The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2000
Filed:
Jun. 30, 1997
Peter A Cohen, Bethesda, MD (US);
Brian J Czerniecki, Haddenfield, NJ (US);
Gary K Koski, Bethesda, MD (US);
David E Weng, Bethesda, MD (US);
Charles Carter, Gaithersberg, MD (US);
John O Ojeifo, Washington, DC (US);
Gretchen N Schwartz, Wheaton, MD (US);
Abstract
The present invention relates to methods of increasing the antigen presenting ability of monocytes by contacting them with an agent which increases the intracellular calcium level. Methods of obtaining the monocytes are also disclosed. In addition, the present invention relates to methods of inducing bone marrow progenitor cells and endothelial cells to express molecules involved in generating immune responses. Methods of modulating the expression of molecules involved in generating immune responses are also disclosed, as are methods of treating cancer and leukemia.