The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2000
Filed:
Mar. 19, 1992
Applicant:
Inventors:
Kiyoshi Nagai, Cambridge, GB;
Hans Christian Tho slashed.gersen, Sawston, GB;
Assignee:
Celltech Therapeutics Limited, Slough, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 697 ; 435 691 ; 435 694 ; 435 696 ; 435 711 ; 4352523 ; 4353201 ; 435471 ; 536 234 ; 536 235 ; 536 2351 ; 536 2353 ;
Abstract
This invention provides a DNA sequence coding for a cleavage site which is specifically cleaved by blood coagulation Factor Xa, a vector containing such a sequence, and a host organism transformed with such a vector. Preferably, in the vector, the Factor Xa cleavage site coding sequence is fused at one end to a product and at its other end to an ATG codon or a sequence coding for at least part of a host protein. This invention also provides a process, for the production of a desired protein or peptide product in native form, comprising: