The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 1999

Filed:

Aug. 19, 1997
Applicant:
Inventors:

Wayne H Schrier, Half Moon Bay, CA (US);

Corey L Jaseph, Mountain View, CA (US);

Ronald J Schoengold, San Jose, CA (US);

Franco Ruggeri, Milan, IT;

Assignee:

Beckman Coulter, Inc., Fullerton, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
436518 ; 422 56 ; 422 58 ; 422 61 ; 422101 ; 435-2 ; 435-4 ; 435-71 ; 435-792 ; 4352871 ; 4352872 ; 4352877 ; 4352878 ; 4352879 ; 435805 ; 435810 ; 435962 ; 435970 ; 436514 ; 436169 ; 436170 ; 436177 ; 436178 ; 436808 ; 436810 ;
Abstract

A device for the separation of the liquid portion of blood from the cellular components of blood comprises: (1) a pad of porous material permeable to the liquid portion of blood but capable of trapping the cellular components of blood; (2) a substrate supporting the pad; and (3) means, attached to the pad, for facilitating the flow of the liquid portion of the blood: (i) through interstices around the trapped cellular components of the blood and (ii) from the pad of porous material. The separation of the liquid portion of blood from the cellular components of the blood occurs by flow through the pad of porous material without significant hemolysis. The device can be incorporated into a device for the performance of specific binding assays such as immunoassays. The pad of porous material can contain an agglutinating agent such as a lectin or an anti-blood cell antibody, or a carbohydrate such as mannitol. Other devices and methods for the separation of the liquid portion of blood from the cellular components of the blood are also disclosed.


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