The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 1999
Filed:
Mar. 14, 1997
Michael D West, San Carlos, CA (US);
Calvin B Harley, Palo Alto, CA (US);
Scott L Weinrich, San Francisco, CA (US);
Catherine M Strahl, San Francisco, CA (US);
Michael J McEachern, San Francisco, CA (US);
Jerry Shay, Dallas, TX (US);
Woodring E Wright, Arlington, TX (US);
Elizabeth H Blackburn, San Francisco, CA (US);
Nam Woo Kim, Sunnyvale, CA (US);
Homayoun Vaziri, Toronto, CA;
Board of Regents, The University of Texas System, Dallas, TX (US);
The Regents of the University of California, Oakland, CA (US);
Geron Corporation, Menlo Park, CA (US);
Abstract
Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to increase or decrease telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity and means are shown for slowing or reversing the loss of telomeric repeats in aging cells.