The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 1999

Filed:

Aug. 14, 1996
Applicant:
Inventors:

Jan Vijg, Newton, MA (US);

Robert Bishop, Newton, MA (US);

Assignee:

Academy of Applied Science, Concord, NH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06F / ; G01N / ; C12P / ; C07H / ;
U.S. Cl.
CPC ...
364497 ; 364496 ; 364499 ; 435 911 ; 435 912 ; 536 2433 ;
Abstract

The invention encompasses a semi-automatic and/or automatic computer-aided technique for designing comprehensive DNA diagnostic tests for mutations in disease genes through searching for optimized conditions for PCR amplification and for optimal melting behavior in denaturing gradient gels and for optimal distribution in two-dimensional electrophoresis display of the mutational target fragments.


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