The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 1999
Filed:
Feb. 24, 1998
Applicant:
Inventors:
Brian C Cunningham, San Bruno, CA (US);
James A Wells, Burlingame, CA (US);
Ross G Clark, Pacifica, CA (US);
Kenneth Olson, Burlingame, CA (US);
Germaine G Fuh, Pacifica, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
514 12 ; 514866 ; 530399 ; 530402 ;
Abstract
Human growth hormone variants are disclosed having enhanced affinity for the growth hormone receptor. Also disclosed are human growth hormone variants conjugated to one or more chemical groups, such as poly(ethylene glycol), which is believed to prolong the in vivo half-life of the variants.