Ultrasound system for contrast agent imaging and quantification in

Abstract

A difference image processing scheme and contrast-only difference image processing scheme is provided for imaging anatomic structures or vessels which have periodic physiological motion that define physiologic cycles. Image data is acquired using ultrasound imaging equipment. In the scheme, a template image is captured at a first time period. The template image comprises image data of a portion of the subject's body acquired at a selected time period during the physiologic cycle. The captured template image is stored. Next, a real-time image is taken at a second time period subsequent to the first time period. The real-time image includes image data of the portion of the subject's body acquired at the same selected time period during the physiologic cycle as the template image. The stored template image and the real-time image are simultaneously displayed on an image display. The simultaneously displayed images have a visually perceptible effect when the real-time image becomes closely aligned with the template image at the same selected time period during the physiologic cycle. After alignment is achieved, a difference image is calculated, stored and displayed. The difference image may be a contrast-only image if a contrast agent has been injected into the imaged region during the second time period. The template image improves the alignment process of pre-contrast and post-contrast images, or pre-event/post-event difference images.