The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 1999
Filed:
Jun. 26, 1998
David M Hilbert, Bethesda, MD (US);
Daniel P Bednarik, Columbia, MD (US);
Bernadetta Nardelli, Gaithersburg, MD (US);
Marianne Murphy, Richmond, GB;
David Parmelee, Rockville, MD (US);
Ann Gronowski, Ballwin, MO (US);
Robert Schreiber, St. Louis, MO (US);
Humn Genome Sciences, Inc., Rockville, MD (US);
Washington University, St. Louis, MO (US);
Abstract
This invention relates to the use of the baculovirus glycoprotein, Interferon Stimulating Protein (ISP) (also known as gp67, gp64 EFP, or gp64), or the gene sequence encoding ISP, to stimulate production of interferon, such as for immunotherapy, anti-viral, anti-cancer, anti-bacterial, or anti-parasitic therapy. This invention also relates to novel mutant forms of ISP that show enhanced biological (i.e., anti-viral) activity, increased stability, higher yield or better solubility.