The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 14, 1999

Filed:

Dec. 02, 1998
Applicant:
Inventors:

Stanley T Crooke, Carlsbad, CA (US);

Walter F Lima, San Diego, CA (US);

Hongjiang Wu, Carlsbad, CA (US);

Assignee:

Isis Pharmaceuticals Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12N / ; C07H / ; C07H / ;
U.S. Cl.
CPC ...
435375 ; 435-6 ; 435 911 ; 435193 ; 4353201 ; 435325 ; 435440 ; 435455 ; 536 231 ; 536 232 ; 536 243 ; 536 2431 ; 536 2433 ; 536 245 ; 536 253 ;
Abstract

The present invention provides polynucleotides and polypeptides encoded thereby of human Type 2 RNase H. Methods of using these polynucleotides and polypeptides in enhancing antisense oligonucleotide therapies are also provided.


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