The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 1999
Filed:
Mar. 10, 1998
Applicant:
Inventors:
Jeffrey B Huff, Park Ridge, IL (US);
Barbara T Merchant, Wilmette, IL (US);
Carolyn R Mullen, Libertyville, IL (US);
Seshagiri R Tata Venkata, Chicago, IL (US);
Assignee:
Abbott Laboratories, Abbott Park, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07D / ;
U.S. Cl.
CPC ...
536-41 ; 549214 ; 549283 ;
Abstract
Fluorescent enzyme substrates are provided. The substrates are derivatives of coumarin having an enzyme cleavable group at position 7 and a hydrophilic amide group at position 4. The compounds are highly water soluble, stable at ambient and reduced temperatures and fluoresce upon cleavage by an enzyme.