The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 1999

Filed:

Apr. 19, 1994
Applicant:
Inventors:

Michael Kriegler, Rancho Santa Fe, CA (US);

Carl Perez, San Diego, CA (US);

Robert F Halenbeck, San Rafael, CA (US);

David A Jewell, Sausalito, CA (US);

Kirston E Koths, El Cerrito, CA (US);

Assignee:

Chiron Corporation, Emeryville, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514 18 ; 530331 ; 530351 ; 53038823 ; 5303892 ; 424 851 ; 4241451 ; 4241581 ;
Abstract

Compounds having proteolytic inhibitory activity useful for treating diseases, particularly as applied to the treatment of sepsis, AIDS or autoimmune diseases, resulting from a decrease in the circulating level of mature protein hormones derived from the proteolytic cleavage of prohormone precursors such as 26 kDProTNF, and methods for identifying compounds having the desired inhibitory activity are provided.


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