The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 1999
Filed:
Jul. 18, 1996
Barton F Haynes, Durham, NC (US);
Alejandro Aruffo, Edmonds, WA (US);
Dhavalkumar D Patel, Durham, NC (US);
Michael A Bowen, Seattle, WA (US);
Hans Marquardt, Mercer Island, WA (US);
Anthony W Siadak, Seattle, WA (US);
Duke University, Durham, NC (US);
Bristol-Myers Squibb Company, New York, NY (US);
Abstract
The present invention relates, in general, to CD6 and, in particular, to a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to methods of inhibiting the interaction of CD6 and the CD6 ligand, and to methods of screening compounds for their ability to inhibit that interaction. The invention also relates to antibodies, and binding fragments thereof, specific for CD6 ligand.