The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 1999

Filed:

Oct. 01, 1996
Applicant:
Inventors:

John Nicholas Whitaker, Birmingham, AL (US);

Robert David Kachelhofer, Birmingham, AL (US);

Beverly Ann Layton, Birmingham, AL (US);

Edwin Luther Bradley, Jr, Birmingham, AL (US);

Sheila Loughran Burgard, Lake Bluff, IL (US);

Anthony Thomas Reder, Oak Park, IL (US);

Wendy Jean Morrison, Vancouver, CA;

Guojun Zhao, Vancouver, CA;

Donald Winston Paty, Vancouver, CA;

Assignee:

UAB Research Foundation, Birmingham, AL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-71 ; 435-71 ; 436501 ; 436504 ; 436536 ; 436540 ; 436542 ; 436804 ; 436811 ;
Abstract

The present invention provides a method of determining the status of a multiple sclerosis patient, i.e., predicting the transition from a status of relapsing-remitting to a progressive phase of multiple sclerosis, comprising the step of measuring the levels of urinary myelin basic protein-like material in the patient. The present invention also provides a method of determining the amount of lesions and total lesion area of a multiple sclerosis patient, comprising the step of measuring the levels of urinary myelin basic protein-like material in the patient. Further provided is a method of monitoring myelination in a developing child, comprising the step of: measuring the levels of myelin basic protein-like material in the urine of said child.


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