The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 1999

Filed:

Sep. 18, 1997
Applicant:
Inventors:

Bryan Whitson, West Lafayette, IN (US);

Boyle Cheng, Greeley, CO (US);

Stephen F Badylak, West Lafayette, IN (US);

Assignees:

Purdue Research Foundation, West Lafayette, IN (US);

Methodist Hospital of Indiana, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F / ; A61F / ;
U.S. Cl.
CPC ...
623 15 ; 623 13 ; 623 66 ; 623 11 ; 623-1 ; 623 12 ; 623 16 ; 600 36 ;
Abstract

A perforated unitary multi-laminar tissue graft construct and method for preparing such construct is described. The method comprises overlapping strips of submucosa tissue with other strips of submucosal tissue, compressing at least the overlapped portions of said strips between two surfaces under conditions that allow or promote dehydration of the compressed submucosa sheets, and perforating the resulting unitary tissue graft construct. The perforated tissue graft compositions have enhanced mechanical and remodeling properties relative to non-perforated submucosal tissue grafts.


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