The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 30, 1999
Filed:
May. 12, 1998
Sumitomo Chemical Company, Limited, Osaka, JP;
Abstract
A process for producing 1-substituted tetrahydroquinazolines represented by the formula (III): ##STR1## wherein Z represents a methylene group which is optionally substituted by an alkyl group; R.sub.6 represents an alkyl group or an aralkyl group; R.sub.1 and R.sub.2 independently represent a hydrogen atom, a halogen atom, a nitro group, an azido group, an alkyl group, an alkenyl group, an aralkyl group, an alkoxy group, an alkoxycarbonyl group, an acyloxygroup, or an amino group represented by XNR.sub.4 R.sub.5 in which X represents a direct bond, an alkylene group or a carbonyl group, and N, R.sub.4 and R.sub.5 may form together a five- or six-membered heterocyclic ring or R.sub.4 and R.sub.5 independently represent an alkyl group or an acyloxy alkyl group; and R.sub.3 represents a hydrogen atom, a halogen atom, a nitro group, an azido group, an alkyl group, an alkenyl group, an aralkyl group,an alkoxy group, or an alkoxycarbonyl group which comprises reacting tetrahydroquinazolines represented by the formula (I): ##STR2## wherein R.sub.1, R.sub.2 and R.sub.3 are as defined above with hexamethyldisilazane; and reacting the resultant product with a chloroalkanoate represented by the formula (II):