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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5994539 B1

PDFFull Text
Date of Patent:
Nov. 30, 1999

Filed:

Dec. 18, 1997

Mercapto acyl aminoacid derivatives endowed with dual ace-nep inhibitory

Applicant:
Inventors:

Franco Pellacini, Milan, IT;

Stefano Romagnano, Buccinasco, IT;

Gabriele Norcini, Vizzola Ticino, IT;

Francesco Santangelo, Milan, IT;

Mario Fantucci, Milan, IT;

Claudio Semeraro, Bresso, IT;

Assignee:

Zambon Group S.p.A., Milan, IT;

Attorney:

Nikaido Marmelstein Murray & Oram LLP

Primary Examiner:

Floyd D Higel

Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ; A61K / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
544224 ; 514247 ; 514256 ; 514357 ; 514365 ; 514378 ; 514439 ; 514471 ; 514513 ; 514532 ; 514534 ; 514570 ; 544335 ; 546340 ; 546342 ; 548204 ; 548240 ; 548247 ; 549 76 ; 549553 ; 558254 ; 558255 ; 560 16 ; 560147 ; 560153 ; 562426 ; 562556 ; 562557 ;
Abstract

Compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula I are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.

Find Patent Forward Citations

Pellacini, Franco. (1999). Mercapto acyl aminoacid derivatives endowed with dual ace-nep inhibitory (U.S. Patent No. 5994539). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5994539

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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