The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 1999

Filed:

Aug. 15, 1997
Applicant:
Inventors:

John E Smart, Weston, MA (US);

Hermann Oppermann, Medway, MA (US);

Engin Ozkaynak, Milford, MA (US);

Thangavel Kuberasampath, Medway, MA (US);

David C Rueger, Hopkinton, MA (US);

Roy H Pang, Etna, NH (US);

Charles M Cohen, Medway, MA (US);

Assignee:

Creative BioMolecules, Inc., Hopkinton, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ;
U.S. Cl.
CPC ...
435354 ; 435325 ;
Abstract

Disclosed is a method of screening candidate compounds for the ability to modulate the level of morphogenic protein in mammalian system. The method includes determining a parameter indicative of the level of production of a morphogenic in a cell culture known to produce the morphogen, incubating a candidate compound with the culture for a time sufficient to allow the compound to affect the production of the morphogenic protein, and then assaying the culture again to detect a change in the level of morphogenic protein production.


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