The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 1999

Filed:

Mar. 27, 1997
Applicant:
Inventors:

Michel Streuli, Brookline, MA (US);

Anne Debant, Padres le Lez, FR;

Carles Serra-Pages, Boston, MA (US);

Assignee:

Dana-Farber Cancer Institute, Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435 691 ; 4353201 ; 435325 ; 536 235 ; 536 2431 ;
Abstract

Nucleic acids encoding TRIO proteins, the TRIO proteins themselves, and active portions thereof as described. In addition, antibodies immunoreactive with TRIO proteins, and preparations of such compositions are provided. Diagnostic and therapeutic assays and reagents for detecting and treating disorders involving, for example, aberrant expression (or loss thereof) of the TRIO protein are described. Assays are provided for identifying agents that modulate the biological function of TRIO proteins.


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