The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 1999
Filed:
Aug. 28, 1997
Applicant:
Inventors:
Corine M Dietz, San Francisco, CA (US);
Jacqueline A Gibbons, Oakland, CA (US);
Eric W Taylor, Oakland, CA (US);
Assignee:
Chiron Corporation, Emeryville, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; A01N / ;
U.S. Cl.
CPC ...
436 63 ; 436124 ; 436503 ; 435-11 ; 435-12 ; 514832 ; 514743 ; 514746 ; 514744 ; 514759 ; 604-4 ;
Abstract
A method for analyzing the ADME/PK properties of a mixture of compounds is (1) perfusing an animal or organ with a perfluorocarbon emulsion blood substitute, (2) administering the mixture of test compounds, (3) withdrawing an aliquot of the perfusate, (4) disrupting the emulsion, and (5) analyzing the aqueous phase of the perfusate for the concentration of test compounds.