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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5985581 B1

PDFFull Text
Date of Patent:
Nov. 16, 1999

Filed:

Jul. 17, 1997

Use of presenilin-1 for diagnosis of alzheimers disease

Applicant:
Inventors:

Ralph A Nixon, Tarrytown, NY (US);

Anne M Cataldo, Nanuet, NY (US);

Benjamin H Kao, New York, NY (US);

Paul M Mathews, Irvington, NY (US);

Assignee:

The McLean Hospital Corporation, Belmont, MA (US);

Attorneys:

Clark & Elbing, LLP.

Bieker-Brady; Kristina

Primary Examiner:

S Mark Clardy

Assistant Examiner:

Michael G Hartley

Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-71 ; 435-792 ; 436 63 ; 436512 ; 436518 ; 436528 ; 436529 ; 436530 ; 436535 ; 436161 ; 436547 ; 436548 ; 436811 ;
Abstract

The invention provides a method of diagnosing Alzheimer's disease. The method utilizes presenilin-1, whose level is found to be substantially decreased in Alzheimer's patients. Included in the invention are diagnostic kits for Alzheimer's disease and methods of screening for effective therapeutics for the disease. The invention also provides a method of studying the function and regulation of presenilin-1 in brain by the use of primate retinoblastoma cells.

Find Patent Forward Citations

Nixon, Ralph. (1999). Use of presenilin-1 for diagnosis of alzheimers disease (U.S. Patent No. 5985581). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5985581

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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